2024-12-14
鑽石生技於2023年投資Syncell（新析生技），Syncell是2020年由中央研究院團隊所衍生新創，發展領域為空間生物學，其核心技術平台 Microscoop® （光標靶儀）是世界上第一個「可抓取式」顯微鏡，應用人工智慧演算法，從指定的細胞位置，可選擇性地抓取蛋白質和核酸進行分析，這項技術於今年（2024年）榮登《The Scientist》2024 年度十大創新榜單，凸顯其在生命科學領域的技術領先地位。
Syncell’s Microscoop® Named One of The Scientist’s Top 10 Innovations of the Year
TAIPEI, Taiwan & WATERTOWN, Mass. – December 13, 2024 – Syncell, a leader in next-generation subcellular protein purification and spatial proteomics analysis, today announced that its Microscoop® was named #5 on The Scientist’s prestigious list of “Top Innovations of 2024.” The list, unveiled today, highlights groundbreaking advancements and tools driving progress in life sciences and biotechnology.
“Our Microscoop platform represents a groundbreaking approach to spatial proteomics, providing researchers with the precision and sensitivity needed to uncover new insights into biological processes,” said Jung-Chi Liao, founder and CEO of Syncell. “We are honored to be recognized by The Scientist for our unique approach to helping researchers take their protein research further, by bringing together different technologies to build innovative models of biology that were previously out of reach.
” Syncell’s Microscoop is an innovative platform designed to enable unbiased spatial proteomic discovery at the disease site, delivering unparalleled precision in identifying novel protein components from targeted regions of interest (ROIs). Utilizing microscopy-guided photochemistry, the Microscoop system photolabels proteins within user-defined ROIs in cells or tissues, enabling the precise extraction of proteins from tens of thousands of fields of view (FOVs) with similar morphological features. This unique capability allows researchers to perform hypothesis-free subcellular protein analysis with exceptional sensitivity and specificity, uncovering both known and novel protein constituents within subcellular structures. By offering unprecedented insights into site-specific proteomes, Microscoop empowers a wide range of biological and translational research.
The Microscoop platform is the first of its kind to combine photochemistry, microscopy, artificial intelligence-driven image processing, mechatronics, and biochemistry into a streamlined and user-friendly system. This enables precise, high-throughput, image-guided protein labeling at submicron resolution, allowing scientists to spatially label and analyze proteins in individual cells or subcellular regions. Photolabeled proteins are extracted and analyzed with mass spectrometry to reveal thousands of known and novel proteins players in disease-relevant or biologically significant ROIs.
By providing a unique and precise approach to spatial proteomics, Microscoop equips researchers with the ability to map and discover the proteomic landscape of cellular and subcellular environments, opening new frontiers in disease research and therapeutic innovation.
To learn more about Microscoop technology, visit www.Syncell.com.
About Syncell
Syncell is a commercial stage life science company focused on subcellular protein purification and spatial proteomics analysis. The company was founded in 2020 leveraging technology developed by founder and CEO Jung-Chi Liao at Academia Sincia laboratory in Taiwan. Headquartered in Taipei, Taiwan and Watertown, Mass., Syncell has commercialized its Microscoop® technology, helping researchers achieve unbiased discovery in spatial proteomics at the disease site, with the ability to accurately discover new protein components from targeted regions of interest. To date, the company has raised $30 million from investors. To learn more, visit www.Syncell.com or follow us on Linkedin.
